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FunDiFunDi is a phylogenetically aware, maximum-likelihood mixture model based prediction program for identifying functionally divergent/specificity determining amino acid residues among/between protein families and sub-families.
Details on the algorithm can be found in the Bioinformatics Publication, currently in Advance Access: FunDi as used in the publication can be downloaded here Current versions of FunDi with bug-fixes are now being maintained at GitHub |